We are looking for costumers or collaborations who need /request analytical laboratory activities on samples derived from patients that underwent Advanced Therapies Medicinal Products (ATMPs) treatment. SR-Tiget Clinical Lab (TCL) is a laboratory that runs tests required for clinical trial endpoints or non-interventional research protocols for ATMPs. It is a certified Phase I Centre and performs analysis for AIFA, EMA, and FDA-approved clinical Trials/research protocols. TCL works under GCLP (Good Clinical Laboratory Practices), GCP (Good Clinical Practices) and follows GLP (Good Laboratory Practices) standards when applies, certified with an ISO 9001 quality system. Listed below some of the available services: - Mononuclear and Granulocytes Cells isolation from Peripheral Blood and Bone Marrow - Positive Selection and Purification of Hematopoietic Stem and progenitor Cells - Positive Selection and Purification of myeloid and lymphoid blood cells - Clonogenic Assay for Hematopoietic Stem Cells Progenitor and Bone Marrow Mononuclear Cells - Number of integrated Lentiviral/Retroviral vector Copies (vector copy number-VCN) in human genomic DNA - Percentage of Transduction and Number of integrated Lentiviral/Retroviral vector Copies (vector copy number-VCN) in CFU (Colony Forming Units) - Immune response to transgene to detect the presence of antibodies against the protein in patient/healthy donor’s plasma sample - Response of T cell in the presence of polyclonal or antigenic stimuli to trigger cell proliferation - Transgene expression in patient/healthy donor’s cells - Transgene enzymatic activity evaluation in patient/healthy donor’s cells - Quantitative analysis of TCR Vβ repertoire in human T lymphocytes Further analytical procedures may be developed and validated upon request and evaluation.