Sirius Analytical Instruments Sirius Analytical offers both instrumentation and CRO services for measurement of pKa, logP/logD, Solubility, Dissolution and Particle properties. Our unique solutions for automated supersaturation measurement reveal new insights about the pH-dependent supersaturation a compound can exhibit and how supersaturation may be enhanced or suppressed via the use of formulation additives and excipients.    Our SiriusT3 instrument offers automated physchem measurements using sub-mg quantities of material on a single integrated hardware platform.   Our Sirius Insight instrument is an innovative particle size & shape analyser which makes measurements easier, more meaningful and robust. Insight utilises two measurement methods: Laser Obscuration Time (LOT) and digital video imaging.   Our Sirius SDI instrument is a break-through in dissolution imaging allowing researchers to look directly at the solid/liquid, semi-solid/liquid or gel/liquid interface as the dissolution process is occurring: real-time UV movies of the dissolution process are displayed - taken just microns from the drug surface.   Our Analytical Service provides a reliable and cost effective source for outsourcing PhysChem measurements and includes all of our formulation testing capabilities. Our expertise in automation and miniaturization means valuable data can be obtained at early stages of pre-formulation and development, improving efficiency and allowing informed decisions to be made earlier in the drug development process.